We report a case of lower leg compartment syndrome caused by low energy trauma in an alcoholic liver cirrhosis patient. The patient was a 65-year-old man who had been alcoholic for 25 years. One day, after walking five minutes, right leg pain gradually emerged. Three days later, he complained of severe leg pain and was taken to hospital by ambulance. He was diagnosised with lower leg hematoma and was treated conservatively but because his symptoms did not improve, he was transferred to our hospital. On arrival, he had strong leg pain and marked swelling of the right leg. Compartment pressure was above 50 mmHg. We could not find the source of bleeding by angiograpy. Because of coagulopathy secondary to liver failure, we were uncertain about how to controlling the bleeding and decided not to operate. After four weeks later, the patient died of liver failure and complications. Cases of compartment syndrome secondary to hematoma in coagulopathic end-stage liver disease patients leading to death are rare. Aggressive surgical treatment shoud be carefully considered.