A Cryptophane Biosensor for the Detection of Specific Nucleotide Targets through Xenon NMR Spectroscopy

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A Cryptophane Biosensor for the Detection of Specific Nucleotide Targets through Xenon NMR Spectroscopy

Roy, Vincent; Brotin, Thierry; Dutasta, Jean-Pierre; Charles, Marie-Hélène; Delair, Thierry; Mallet, François; Huber, Gaspard; Desvaux, Hervé; Boulard, Yves; Berthault, Patrick

Chemphyschem, October 8, 2007, Volume: 8, Issue: 14

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DNA sensor: A xenon host composed of a cryptophane structure with a DNA strand (see picture) serves to detect its complementary strand in the micromolar range through laser‐polarized 129Xe NMR spectroscopy.

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