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Luo, Yvonne H-L; da Cruz, Lyndon
British medical bulletin, 03/2014, Volume: 109, Issue: 1Journal Article
The Argus® II is the first retinal prosthesis approved for the treatment of patients blind from retinitis pigmentosa (RP), receiving CE (Conformité Européenne) marking in March 2011 and FDA approval in February 2013. Alpha-IMS followed closely and obtained CE marking in July 2013. Other devices are being developed, some of which are currently in clinical trials. A systematic literature search was conducted on PubMED, Google Scholar and IEEExplore. Retinal prostheses play a part in restoring vision in blind RP patients providing stable, safe and long-term retinal stimulation. Objective improvement in visual function does not always translate into consistent improvement in the patient's quality of life. Controversy exists over the use of an external image-capturing device versus internally placed photodiode devices. The alpha-IMS, a photovoltaic-based retinal prosthesis recently obtained its CE marking in July 2013. Improvement in retinal prosthetic vision depends on: (i) improving visual resolution, (ii) improving the visual field, (iii) developing an accurate neural code for image processing and (iv) improving the biocompatibility of the device to ensure longevity.
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