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Abram, Maja; Magaš, Morana; Škrobonja, Ivana; Barać, Nives
Medicina fluminensis, 12/2020, Volume: 56, Issue: 4Journal Article
Transplantirani i ostali urološki pacijenti imaju češće potrebu za uvođenjem ureteralnog stenta, odnosno urinarnih katetera, te su izloženi povećanom riziku za stjecanje infekcija mokraćnog sustava (IMS). To je najčešća infektivna komplikacija u primatelja alogeničnog grafta, glavni izvor pijelonefritisa, bakterijemije i sepse. Također, IMS su najzastupljenije infekcije povezane sa zdravstvenom skrbi, a glavni rizični čimbenik za njihov nastanak je upravo prisustvo katetera. Vodeći uzročnici ovih infekcija su E. coli, E. faecalis, vrste iz roda Klebsiella, Proteus i Pseudomonas koje često karakterizira i višestruka antimikrobna rezistencija, što dodatno ugrožava klinički ishod. Radi praćenja IMS-a povezanih s uporabom katetera svake se godine provodi jednodnevno presječno istraživanje kojim su obuhvaćeni svi pacijenti hospitalizirani taj dan. Rezultati pridonose sagledavanju problema, unaprjeđenju mjera prevencije, planiranju empirijske antimikrobne terapije, odnosno sigurnosti hospitaliziranih uroloških pacijenata. Transplanted and other urological patients are more likely to need a ureteral stent, or urinary catheters, and are at increased risk of acquiring urinary tract infections (UTI). It is the most common infectious complication in the recipient of allogeneic graft, the main source of pyelonephritis, bacteremia and sepsis. Also, UTIs are the most common healthcare associated infections, and the main risk factor for their occurence is the use of urinary catheters. The leading agents of these infections are E. coli, E. faecalis, species of the genus Klebsiella, Proteus and Pseudomonas, often characterized by multiple antimicrobial resistance, further compromising clinical outcome. To monitor the catheter associated UTI, a one-day point-prevalence study is conducted every year, covering all patients hospitalized that day. The results contribute to the understanding of the problem, improvement of prevention measures, planning of empirical antimicrobial therapy, that is, the safety of hospitalized urological patients.
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