Using deep Subaru/Faint Object Camera And Spectrograph (FOCAS) spectra of 34 H ii regions in both the inner and outer parts of the extended ultraviolet (XUV) disc galaxy NGC 4625 we have measured an abundance gradient out to almost 2.5 times the optical isophotal radius. We applied several strong line abundance calibrations to determine the H ii region abundances, including R 23, N ii/O ii, N ii/Hα as well as the O iii λ4363 auroral line, which we detected in three of the H ii regions. We find that at the transition between the inner and outer disc the abundance gradient becomes flatter. In addition, there appears to be an abundance discontinuity in proximity of this transition. Several of our target H ii regions appear to deviate from the ionization sequence defined in the N ii/Hα versus O iii/Hβ diagnostic diagram by bright extragalactic H ii regions. Using theoretical models we conclude that the most likely explanations for these deviations are either related to the time evolution of the H ii regions or stochastic variations in the ionizing stellar populations of these low-mass H ii regions, although we are unable to distinguish between these two effects. Such effects can also impact on the reliability of the strong line abundance determinations.