Purpose of Review Social media platforms such as Twitter are increasingly utilized to interact, collaborate, and exchange information within the academic medicine community. However, as Twitter begins to become formally incorporated into professional meetings, educational activities, and even the consideration of academic promotion, it is critical to better understand both the benefits and challenges posed by this platform. Recent Findings Twitter use is rising amongst healthcare providers nationally and internationally, including in the field of hematology and oncology. Participation on Twitter at national conferences such as the annual meetings of American Society of Hematology (ASH) and American Society of Clinical Oncology (ASCO) has steadily increased over recent years. Tweeting can be used advantageously to cultivate opportunities for networking or collaboration, promote one’s research and increase access to other’s research, and provide efficient means of learning and educating. However, given the novelty of this platform and little formal training on its use, concerns regarding patient privacy, professionalism, and equity must be considered. Summary These new technologies present unique opportunities for career development, networking, research advancement, and efficient learning. From “tweet ups” to Twitter journal clubs, physician-scientists are quickly learning how to capitalize on the opportunities that this medium offers. Yet caution must be exercised to ensure that the information exchanged is valid and true, that professionalism is maintained, that patient privacy is protected, and that this platform does not reinforce preexisting structural inequalities.