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Fernández-Rojas, Miguel A.; Luna-Ruiz Esparza, Marco A.; Campos-Romero, Abraham; Calva-Espinosa, Diana Y.; Moreno-Camacho, José L.; Langle-Martínez, Ariadna P.; García-Gil, Abraham; Solís-González, Claudia J.; Canizalez-Román, Adrián; León-Sicairos, Nidia; Alcántar-Fernández, Jonathan
International journal of infectious diseases, 03/2021, Volume: 104Journal Article
•High COVID-19 incidence was observed in working-age Mexican outpatients.•Logistics or delivery jobs have a higher risk of SARS-CoV-2 infection.•Three symptomatic profiles were identified in COVID-19 patients.•Presymptomatic people were more frequent among elders than among young individuals.•Different epidemiologic profiles were found between symptomatic and presymptomatic. The COVID-19 diagnosis is difficult and ambiguous due to nonspecific symptoms. Further, data from Mexico arehospitable population-based without signs and symptoms information. Thus, this work aims to provide epidemiology information about the burden of COVID-19 in Mexican outpatients and to identify symptomatic COVID-19 profiles that could help in the early diagnosis of the disease. From June to September, epidemiological, clinical, and demographic data of 482,413 individuals diagnosed by RT-PCR test for SARS-CoV-2 in Salud Digna clinics were collected. We observed a 41% incidence of SARS-CoV-2 infections with a mean age of 36 years and with young adults (20–40 years) being the most affected. Among occupations, delivery persons (OR 1.38) or informal traders (OR 1.33) had a higher risk of COVID-19. Moreover, 13% of SARS-CoV-2 infections were in presymptomatic patients. Finally, we identified three different symptomatic profiles (common, respiratory, and gastrointestinal) associated with COVID-19. The incidence of SARS-CoV-2 was high among outpatients with a significant proportion of presymptomatic carriers, and thus it is necessary to increase testing and continue SARS-CoV-2 surveillance with a better description of signs and symptoms; in this regard, we identified three symptomatic profiles that could help in the diagnosis of COVID-19.
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