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Armstrong-James, Darius; Youngs, Jonathan; Bicanic, Tihana; Abdolrasouli, Alireza; Denning, David W; Johnson, Elizabeth; Mehra, Varun; Pagliuca, Tony; Patel, Brijesh; Rhodes, Johanna; Schelenz, Silke; Shah, Anand; van de Veerdonk, Frank L; Verweij, Paul E; White, P Lewis; Fisher, Matthew C
The European respiratory journal, 10/2020, Volume: 56, Issue: 4Journal Article
The coronavirus disease 2019 (COVID-19) virus caused a wide spectrum of disease in healthy individuals, as well as those with common comorbidities 1. Severe COVID-19 is characterised by acute respiratory distress syndrome (ARDS) secondary to viral pneumonitis, treatment of which may require mechanical ventilation or extracorporeal membrane oxygenation 2. Clinicians are alert to the possibility of bacterial co-infection as a complication of lower respiratory tract viral infection; for example, a recent review found that 72% of patients with COVID-19 received antimicrobial therapy 3. However, the risk of fungal co-infection, in particular COVID-19 associated pulmonary aspergillosis (CAPA), remains underappreciated. Cases of COVID-19 associated pulmonary aspergillosis (CAPA) are being increasingly reported and physicians treating patients with COVID-19-related lung disease need to actively consider these fungal co-infections https://bit.ly/3feuGsQ
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