The prescission neutron multiplicities (νpre) are studied for a systematic understanding of the influence of entrance-channel shell closure in fusion-fission dynamics. The existing νpre data are analyzed for reactions with a wide variety of target and projectile combinations. For completeness, the measured νpre data for the fusion-fission reactions with the doubly closed shell 16O projectile on the targets having either proton (204,206Pb) or both proton and neutron (208Pb) shell closure is reanalyzed. Although the measured νpre for 224Th disagree with the available data reported by Rossner et al. (1992) 1, our results are found to be more consistent and follow a systematic trend as described in this letter. Theoretical analysis is performed within the standard statistical model framework, where dissipation strength is used as a tunable parameter. It is observed that irrespective of the compound nuclear excitation energy, the entrance channel magicity imparts an intriguing impact on the dissipation strength. A similar entrance channel effect in the evaporation residue cross-section is also demonstrated. In conclusion, the present analysis establishes an entanglement of the exit channel observables with the entrance channel shell closure. It contradicts the hypothesis of complete equilibrium in compound nuclear reactions. •Dissipation transiently drives the fission degree of freedom and delays the journey of CN across the fission barrier.•A systematic analysis of the existing prescission neutron multiplicity data is performed.•Systematic analysis reveals an evident impact of entrance channel magicity on neutron emission.