Human skin dendritic cells in health and disease

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Human skin dendritic cells in health and disease

Haniffa, Muzlifah; Gunawan, Merry; Jardine, Laura

Journal of dermatological science, 02/2015, Volume: 77, Issue: 2

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Highlights • Human skin dendritic cells (DCs) are heterogenous and functionally specialised. • Factor XIIIa+ dermal dendrocytes are resident dermal macrophages. • Dermal CD14+ cells, previously defined as DCs, are monocyte-derived macrophages. • Dynamic changes occur in the composition of recruited ‘inflammatory’ DCs and resident DCs in inflamed skin.

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Haniffa, Muzlifah | Gunawan, Merry | Jardine, Laura

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