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Jabeen, Kauser; Shakoor, Sadia; Hasan, Rumina
International journal of infectious diseases, 03/2015, Volume: 32, Issue: CJournal Article
Highlights • Fluoroquinolones (FQs) are essential anti-tuberculosis drugs, and regimens containing FQs are increasingly explored and are effective. • FQ resistance among Mycobacterium tuberculosis complex isolates is increasing in high-burden countries. • High-burden countries also have weak healthcare systems, which help propagate FQ resistance through omission of regulatory policies and commission of irresponsible drug use. • Drug regulatory agencies as well as other healthcare policymakers and stakeholders must ensure responsible use of FQs to counter increasing drug resistance. • One Health Initiative models work best in preventing FQ misuse in the non-healthcare environment.
