E-resources
-
Akdis, Mübeccel, MD, PhD; Aab, Alar, MSc; Altunbulakli, Can, MSc; Azkur, Kursat, DVM; Costa, Rita A., MSc; Crameri, Reto, PhD; Duan, Su, MD; Eiwegger, Thomas, MD; Eljaszewicz, Andrzej, PhD; Ferstl, Ruth, PhD; Frei, Remo, PhD; Garbani, Mattia, PhD; Globinska, Anna, MSc; Hess, Lena, MD; Huitema, Carly, PhD; Kubo, Terufumi, MD; Komlosi, Zsolt, MD; Konieczna, Patricia, PhD; Kovacs, Nora, MD; Kucuksezer, Umut C., PhD; Meyer, Norbert, MD; Morita, Hideaki, MD; Olzhausen, Judith, PhD; O'Mahony, Liam, PhD; Pezer, Marija, PhD; Prati, Moira, MSc; Rebane, Ana, PhD; Rhyner, Claudio, PhD; Rinaldi, Arturo, MSc; Sokolowska, Milena, MD, PhD; Stanic, Barbara, PhD; Sugita, Kazunari, MD; Treis, Angela, PhD; van de Veen, Willem, PhD; Wanke, Kerstin, PhD; Wawrzyniak, Marcin, PhD; Wawrzyniak, Paulina, MSc; Wirz, Oliver F., MSc; Zakzuk, Josefina Sierra, MD; Akdis, Cezmi A., MD
Journal of allergy and clinical immunology, 10/2016, Volume: 138, Issue: 4Journal Article
There have been extensive developments on cellular and molecular mechanisms of immune regulation in allergy, asthma, autoimmune diseases, tumor development, organ transplantation, and chronic infections during the last few years. Better understanding the functions, reciprocal regulation, and counterbalance of subsets of immune and inflammatory cells that interact through interleukins, interferons, TNF-α, and TGF-β offer opportunities for immune interventions and novel treatment modalities in the era of development of biological immune response modifiers particularly targeting these molecules or their receptors. More than 60 cytokines have been designated as interleukins since the initial discoveries of monocyte and lymphocyte interleukins (called IL-1 and IL-2, respectively). Studies of transgenic or gene-deficient mice with altered expression of these cytokines or their receptors and analyses of mutations and polymorphisms in human genes that encode these products have provided essential information about their functions. Here we review recent developments on IL-1 to IL-38, TNF-α, TGF-β, and interferons. We highlight recent advances during the last few years in this area and extensively discuss their cellular sources, targets, receptors, signaling pathways, and roles in immune regulation in patients with allergy and asthma and other inflammatory diseases.
Author
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
If the library membership card is not in the list,
add a new one.
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|
Source: Personal bibliographies
and: SICRIS
The material is available in full text. If you wish to order the material anyway, click the Continue button.