E-resources
Peer reviewed
Open access
-
Basavaiah, Kanakapura; Somashekar, Bankavadi Chikkaswamy
Eclética química, 03/2018, Volume: 32, Issue: 1Journal Article
Two simple, rapid and cost-effective methods based on titrimetric and spectrophotometrictechniques are described for the assay of RNH in bulk drug and in dosage forms using silver nitrate, mer-cury(II)thiocyanate and iron(III)nitrate as reagents. In titrimetry, an aqueous solution of RNH is treatedwith measured excess of silver nitrate in HNO 3 medium, followed by determination of unreacted silvernitrate by Volhard method using iron(III) alum indicator. Spectrophotometric method involve the addi-tion a known excess of mercury(II)thiocyanate and iron(III)nitrate to RNH, followed by the measurementof the absorbance of iron(III)thiocyante complex at 470 nm. Titrimetric method is applicable over 4-30mg range and the reaction stoichiometry is found to be 1:1 (RNH: AgNO 3 ). In the spectrophotometricmethod, the absorbance is found to increase linearly with concentration of RNH which is corroboratedby the correlation coefficient of 0.9959. The system obey Beer’s law for 5-70 μg mL -1 . The calculatedapparent molar absorptivity and sandell sensitivity values are found to be 3.27 × 10 3 L mol -1 cm -1 , 0.107μg cm -2 respectively.
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
If the library membership card is not in the list,
add a new one.
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|
Source: Personal bibliographies
and: SICRIS
The material is available in full text. If you wish to order the material anyway, click the Continue button.