We present relative astrometric measurements of visual binaries made during the first semester of 2005, with the Pupil Interferometry Speckle Camera and Coronagraph (PISCO) at the 102-cm Zeiss telescope of the Brera Astronomical Observatory, in Merate. We performed 214 new observations of 192 objects, with angular separations in the range 0.2–4.3 arcsec, and with an average accuracy of 0.01 arcsec. Most of the position angles could be determined without the usual 180° ambiguity, and their mean error is . Our sample contains orbital couples as well as binaries whose motion is still uncertain. The purpose of this long-term programme is to improve the accuracy of the orbits and constrain the masses of the components. For the first time with PISCO, the astrometric calibration was made with a grating mask mounted at the entrance of the telescope. The advantage of this procedure is to provide a reliable and fully independent scale determination. We have found two possible new triple systems: ADS 7871 and KUI 15. We propose a preliminary orbit for ADS 4208.