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Potrykus, Joanna; Ballou, Elizabeth R; Childers, Delma S; Brown, Alistair J P
PLOS pathogens, 03/2014, Volume: 10, Issue: 3Journal Article
Furthermore, toxic excess of a non-native metal can displace the native metals from metalloproteins or inhibit the function of non-metalloproteins. ...the levels of iron, copper, and zinc and their partitioning within the body must be tightly regulated to maintain cellular homeostasis whilst avoiding cellular damage. ...in the act of depriving fungal pathogens of nutrients to limit their growth, the host can trigger virulence factors that may exacerbate fungal disease.
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