High-sensitive Troponin I in acute cardiac conditions: Implications of baseline and sequential measurements for diagnosis of myocardial infarction

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High-sensitive Troponin I in acute cardiac conditions: Implications of baseline and sequential measurements for diagnosis of myocardial infarction

Gassenmaier, Tobias; Buchner, Stefan; Birner, Christoph; Jungbauer, Carsten G; Resch, Markus; Debl, Kurt; Endemann, Dierk H; Riegger, Guenter A.J; Lehn, Petra; Schmitz, Gerd; Luchner, Andreas

Atherosclerosis, 05/2012, Volume: 222, Issue: 1

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Highlights ► Baseline and sequential hsTnI was assessed in patients with acute cardiac condition and catheterization. ► hsTnI is a sensitive, albeit unspecific marker of myocardial infarction. ► Relevant elevations of hsTnI also occur in patients with non-ischemic cardiac disease. ► Serial assessment and higher cutpoints increase sensitivity/specificity of hsTnI for NSTEMI. ► A clinical algorithm and concentration intervals for hsTnI are proposed which improve predictive values of hsTnI.

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