Calcifying odontogenic cyst (COC) is an uncommon intraosseous lesion with almost equal frequency in the maxilla and mandible. Therefore, we report a case of a 17-year-old male presenting with a painless swelling on the left hemiface. A computed tomography exam revealed a well-defined unilocular radiolucency with focal areas of radiopacity associated with an impacted upper left lateral incisor, extending from the apical region of tooth 62 posteriorly to the left maxillary sinus. An incisional biopsy was performed, and the histopathologic analysis was characterized by a cystic lesion lined by ameloblastoma-like epithelium with the presence of ghost cells and calcifying material consistent with the diagnosis of COC. The patient was referred for surgical treatment and removal of the impacted tooth, under general anesthesia. Patient recovery was uneventful, and no signs of recurrence were observed in the follow-up. COC is a benign odontogenic lesion with a good prognosis when surgically excised.