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  • Preclamol and parkinsonian fluctuations
    Pirtošek, Zvezdan, 1956- ...
    Preclamol, the (-)enantiomer of 3-PPP (=3(3-hydroxyphenyl)-N- n-propyl piperidine), has a selective dopamine autoreceptor- and postsynaptic mixed agonist-antagonist profile. Its action on patients ... with disabling on-off parkinsonian fluctuations has been studied and compared with those of placebo and subcutaneous apomorphine. Preclamol had a mild but unequivocal antiakinetic effect, less than that caused by subcutaneous apomorphine, but itprovoked less dyskinesia. Further studies to explore the therapeutic potential of preclamol seem justified.
    Vir: Clinical neuropharmacology. - ISSN 0362-5664 (Letn. 16, št. 6, 1993, str. 550-554)
    Vrsta gradiva - članek, sestavni del
    Leto - 1993
    Jezik - angleški
    COBISS.SI-ID - 10005209

vir: Clinical neuropharmacology. - ISSN 0362-5664 (Letn. 16, št. 6, 1993, str. 550-554)
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