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  • Stabilizacijski odmerki metadona in obstanek v obravnavi oseb, odvisnih od heroina, s pridruženo motnjo razpoloženja = Methadone stabilization dosages and retention in treatment in heroin addicts with axis psychiatric comorbidity for mood disorders
    Lovrečič, Mercedes ...
    Background. Heroin addicts with comorbid mood disorder have less favorable prognosis in present treatment programes. The aim of our study was to find outthe differences between group of heroin ... addicts with comorbid mood disorderand group of heroin addicts without psychiatry comorbidity. Patients and methods. Opioid-dependent subjects with comorbid mood disorder and subjectwithout comorbidity were included. They were followed up 990 days and doses of methadone and retention in treatment were recorded. The life table statistical method was used. Results. We studied 76 opioid-dependent subjects,24 with cumorbid mood disorder. There were statisticaly significant diferences between these two groups regarding the methadone dose required for clinical stabilization. Patients with comorbid mood disorders required high eraverage stabilization dose during methadone maintenance treatment (135 mg/day) compared to subject without comorbidity (99 mg/day). During the study period there was no difference in retention in treatment between the two groups of patients. Conclusions. Heroin addicts with comorbid rnood disorder had better retention rate in metadone treatment programe whether the stabilization methadone dosage is adjusted.
    Vrsta gradiva - članek, sestavni del
    Leto - 1999
    Jezik - slovenski
    COBISS.SI-ID - 10546393