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  • The deterioration of cardiovascular reflexes in Parkinson's disease
    Mesec, Anton ...
    Objectives - We have investigated the determination of cardiovascular reflexesin Parkinson's disease. Patients and methods - In a group of 20 patients with Parkinson's disease (PD) and in a group of ... 10 age-matched control subjects a battery of cardiovascular reflex (CVR) tests (Valsalva manoeuvre, deep breathing test, handgrip test, orthostatic test) was repeated after 3 years. Results - In PD patients at deep breathing test, at Valsalva manoeuvre nad at orthostatic test the heart rate response decreased significantly (P<0.05). The impairment of systolic and diastolic blood pressure response at orthostatic test was significant as well (P<0.005). At hand grip test no significant changes in heart rate and blood pressure response were found. In control subjects only heart rate response at orthostatic test decreased significantly after 3 years. Conclusion - Our results show progression of an impairment of sympathetic and parasympathetic control of the cardiovascular functions in patients with PD over a period of 3years.
    Vir: Acta Neurologica Scandinavica. - ISSN 0001-6314 (Letn. 100, 1999, str. 296-299)
    Vrsta gradiva - članek, sestavni del
    Leto - 1999
    Jezik - angleški
    COBISS.SI-ID - 10547673

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