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  • Prognostic value of ultrasonic findings of periventricular hyperechogenicity in preterm neonates
    Burja, Silva, 1942-
    During a four-year period, 70 surviving preterm infants of 32 weeks of gestation or less were prospectively examined by cerebral ultrasonography for the diagnosis and evolution of periventricular ... hyperechogenicity. The aim of this study was to assess the clinical significance of periventricular hyperechogenicity by correlating ultrasound findings and neurodevelopmental outcome of children examined by the age of 1-4 years. During the neonatal period, 12 (17%) cases of extensive periventricular asymmetrical and symmetrical hyperechogenicity were recorded. By subsequent examination, ultrasound appearance of cavitation, mostly in the parieto-occipital region, developed in nine out of 12 children with periventricular hyperechogenicity. By the age of 6 months involution of the cysts occurred with mild or moderate dilatation of lateral ventricles in six out of nine infants with macrocystic transformation of periventricular hyperechogenicity. In the remaining three children, defects of periventricular white matter parenchyma, i.e. porencephalies, persisted. Periventricular hyperechogenicity did not change onsubsequent ultrasound examination in three out of 12 children presenting non-cavitating periventricular leukomalacia. Neurodevelopmental outcome in theexamined children was related to the localization, type and size of periventricular leukomalacia. The children with lesions of the occipital periventricular white matter and those with bilateral cavitating lesions demonstrated severe neurodevelopmental sequelae (e.g., cerebral palsy, visual disorders). Contrary to this, unilateral, frontal, non-cavitating or smaller cystic periventricular leukomalacia have relatively favorable prognosis. For reliable prognosis and qualitative evaluation of the structural hypoxic-ischemic brain lesion in preterm infants, it is necessary to perform accurate timing of ultrasound examinations.
    Vir: Neurologia Croatica : journal of clinical neuroscience. - ISSN 0353-8842 (Letn. 42, št. 2, 1993, str. 145-159)
    Vrsta gradiva - članek, sestavni del
    Leto - 1993
    Jezik - angleški
    COBISS.SI-ID - 11744217

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