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  • Collision tumour in the pelvic cavity: rectal leiomysarcoma and prostate adenocarcinoma
    Pavelić, Jasminka ...
    We report a rare and, to our knowledge, as yet u derscribed type of collision tumour - rectal leiomyosarcoma and prostate adenocarcinoma. Our study also provides the first data on molecular ... alterations (polymerase chain reaction/loss of heterozygosity (LOH) analysis) of the APC, NF-1, DCC, p53, nm23-H1 and BRCA-1 genes in the two components of the collision tumour. None of the genes examined in this study expressed LOH in the prostate carcinoma component of the collision tumour. By contrast, in the leiomyosarcoma component, LOH was found at the DCC and p53 genes, proving that these two tumours did not arise from the same stem cell but represent two different neoplastic growths.
    Vir: Journal of cancer research and clinical oncology. - ISSN 0171-5216 (Letn. 126, št. 2, 2000, str. 95-100)
    Vrsta gradiva - članek, sestavni del
    Leto - 2000
    Jezik - angleški
    COBISS.SI-ID - 12168153

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