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  • Mouse urothelial cells in early postnatal development - proliferation and apical plasma membrane specialization
    Erman, Andreja ; Jezernik, Kristijan
    The purpose of this work was to investigate proliferation and differentiation of the mouse urothelial cells from the day of birth until the 5th postnatal day. The expression of proliferating cell ... nuclear antigen (PCNA) was studied immunocytochemically and the differentiation of apical plasma membrane of superficial cells was analysed by scanning microscopy. It was established thatproliferation activity is very high during all five days since PCNA positive cells are seen in the superficial and in basal cell layer of the urothelium. Results of scanning microscopy show that the differentiation of superficial urothelial cells is a nonsynchronous process, which gradually progresses from the day of birth and leads into homogeneous population of terminally differentiated superficial cells on the 5th postnatal day.
    Vir: Pflügers Archiv : european journal of physiology. - ISSN 0031-6768 (Letn. 440, št. 5, suppl., 2000, str. R183-R184)
    Vrsta gradiva - prispevek na konferenci
    Leto - 2000
    Jezik - angleški
    COBISS.SI-ID - 12194265