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  • Ali je dojenje varno tudi pri jemanju visokih odmerkov metadona (prikaz primera) = Is breast-feeding save even with high-dose methadone treatment? (a case report)
    Bregant, Lev
    Neonatal narcotic abstinence syndrome (NNAS) is a frequent complication in thenewborns of mothers who have been receiving methadone during pregnancy. A positive correlation has been found between the ... severity of withdrawal signs and the dose of the drug used. The signs of NNAS are the consequence of an exaggerated excitement of the central nervous system. The aim of treatment is to calm the newborn wiih the lowest sedation possible. To achieve this we recommend morphine and phenobarbital as the first choice or a combination of both following a scheme formulated in accord with the severity of the withdrawal signs. We report on a case of a mature newborn baby girl with NNAS whose mother was on a high-dose methadone maintenance program during pregnancyand after delivery (115 mg daily). The new-born developed mild signs of the withdrawal syndrome on the first day after birth. After a transient improvement, a heavy abstinence crisis developed on the third day of life, despite breast-feeding and medical treatment with barbiturates and valium. Methadone was not detected in the newborn's serum, but traces were found in her urine. The amount of methadone received through breast-feeding was too small to prevent the occurrence of the withdrawal syndrome. In addition, it did not have a narcotic effect on the newborn. We are therefore of the opinionthat despite high doses of methadone. the mother may breast-feed her baby. Since the amount of methadone received through breast milk is too small to prevent withdrawal signs, the use of morphine preparations according to a scheme is recommended.
    Vir: Odvisnosti : teorija, praksa, raziskovanje. - ISSN 1580-3708 (Letn. 1, št. 1/2, maj 2000, str. 36-38)
    Vrsta gradiva - članek, sestavni del
    Leto - 2000
    Jezik - slovenski
    COBISS.SI-ID - 12482777

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