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Carotid intima-media thickness of young coronary patientsVrtovec, Bojan, 1972- ...Background: Although a greater than normal intima-media thickness (IMT) has been found in older coronary patients, the data for younger patients are lacking. Objective: To determine the carotid IMT ... in patients with premature myocardial infarction. Methods: We measured IMT (common and internal carotid, carotid bifurcation) in 30 coronary patients, aged 30-50 years (mean 46 years), who had survived myocardial infarctions 1-9 years (mean 6 years) earlier, and in 30 age-matched men without clinically evident coronary heart disease (controls) by B-mode ultrasonography. Blood levels of lipoproteins, glucose, iron and transferrin, fibrinogen, tissue plasminogen activator (t-PA)antigen level and activity and plasminogen activator inhibitor (PAI-1) antigen level and activity were also determined. Results: IMT in all segments of carotid arteries in the patients was significantly greater than that in thecontrols (P < 0.0001). The presence of atherosclerotic plaques was correlated to greater than normal carotid IMT. Other risk factors displaying statistically significant correlations to mean carotid IMT were t-PA antigen level and activity, PAI-1 antigen level and level of high-density lipoprotein cholesterol. Conclusions: The significant association between carotid IMT and coronary heart disease suggests that carotid and coronary atherosclerosis evolve simultaneously. Hence carotid IMT can be used as a predictor of coronary atherosclerosis.Vir: Coronary artery disease. - ISSN 0954-6928 (Letn. 10, št. 6, 1999, str. 407-411)Vrsta gradiva - članek, sestavni delLeto - 1999Jezik - angleškiCOBISS.SI-ID - 13297113
Avtor
Vrtovec, Bojan, 1972- |
Keber, Irena |
Gadžijev, Andrej |
Bardorfer, Igor |
Keber, Dušan, 1947-
Teme
Myocardial infarction |
Ultrasonography |
Etiology |
Blood |
Carotid artery, common |
Ultrasonography |
Carotid artery, internal |
Ultrasonography |
Adult |
Middle age |
Blood glucose |
Plasminogen activator inhibitor 1 |
Alteplase |
Lipoproteins, HDL cholesterol |
Iron |
Blood |
Fibrinogen |
Coronary arteriosclerosis |
Ultrasonography |
Blood |
Complications
Vnos na polico
Trajna povezava
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Faktor vpliva
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Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Vrtovec, Bojan, 1972- | 18826 |
Keber, Irena | 00365 |
Bardorfer, Igor | 02929 |
Keber, Dušan, 1947- | 00373 |
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