VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
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Postnatal restoration of the mouse urinary bladder urotheliumErman, Andreja ...Mouse urothelium is disrupted just before birth, followed by a postnatal restoration process which includes cell proliferation, death and differentiation. We assessed urothelial proliferation by the ... expression of proliferating cell nuclear antigen (PCNA), desquamation by electron microscopy, and apoptosis by TUNEL staining and urothelial differentiation by the expression of uroplakins and cytokeratin 20 (CK20) as well as the apical plasma membrane maturation. Our results indicated that urothelial proliferation was high from birth until about the 14th postnatal day. A majority of basal cells and even occasional superficial cells were PCNA positive during the first 5 postnatal days. Cell death occurred during the first 9 postnatal days. Between birth and day 5, single cells underwent apoptosis, whereas between days 6 and 9 cells mainly desquamated. CK20 and uroplakins were expressed in all superficial cells in postnatal urothelium. Their subcellular distribution characteristically changed in accordance with the progressive differentiation of superficial cells. During the urothelial postnatal development, proliferation activity slowly decreases to the proliferatively quiescent urothelium of the adult animal. Apoptosis is presentin the first 9 postnatal days and within a few days of this period it appears simultaneously with desquamation. Superficial urothelial cells gradually differentiate, which is reflected in the changeable morphology of the apical plasma membrane.Vir: Histochemistry and cell biology. - ISSN 0948-6143 (Letn. 115, št. 4, 2001, str. 309-316)Vrsta gradiva - članek, sestavni delLeto - 2001Jezik - angleškiCOBISS.SI-ID - 13914585
Avtor
Erman, Andreja |
Jezernik, Kristijan |
Štiblar-Martinčič, Draga |
Romih, Rok |
Veranič, Peter
Teme
Bladder |
Ultrastructure |
Anatomy and histology |
Urothelium |
Proliferating cell nuclear antigen |
Apoptosis |
Mice |
Cell division |
Microscopy, electron |
Animals, newborn |
Histocytochemistry
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Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Erman, Andreja | 23916 |
Jezernik, Kristijan | 05277 |
Štiblar-Martinčič, Draga | 07798 |
Romih, Rok | 11654 |
Veranič, Peter | 08279 |
Vir: Osebne bibliografije
in: SICRIS
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