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  • Method for designing a vaccine : EP 3 081 229 A1 : applic. no.: 14830810.9, WO 2015/082745
    Legarreta Solaguren, Leire ...
    Computational procedure for designing a vaccine for a disease that starting: - from a plurality of amino acid S 1 ...S k chains obtained from patients infected with such disease; and, - from a T set ... of target epitopes, each epitope being an amino acid chain; comprises the steps of: i) obtaining by means of a combinatory optimization method a plurality of amino acid chains as short as possible with respect to the combinatory optimization method used having as sub-chains at least a integer of epitopes of the T set in each one of the S i sequences, having a value such that the length of the resulting chain is long enough for eliciting an immune response, but not too long so as to elicit an autoimmune response; ii) choosing from the plurality of chains obtained in the previous step at least one final immunogen candidate by at least one standard experimental method; iii) developing the vaccine from said immunogen.
    Vrsta gradiva - patentna prijava ; neleposlovje za odrasle
    Založništvo in izdelava - [München] : European Patent Office, 2016
    Jezik - angleški
    COBISS.SI-ID - 1539018692

Nobena knjižnica v sistemu COBISS.SI nima izvoda tega gradiva.
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