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The localization of oxytocin, vasopressin, somatostatin and luteinizing hormone releasing hormone in the rat neurohypophysisLeeuwen, W. van ...The hypothalamic hormones arginine-vasopressin (AVP), oxytocin (OXT), somatostatin (SOM), and luteinizing hormone-releasing hormone (LHRH) were localized in the rat neurohypophysis by the use of ... semithin serial sections and the unlabeled antibody enzyme method. Clusters of AVP fibres are present within the central region of the neural lobe, clusters of OXT fibres mainly in the peripheral part. The AVP fibres enter bilaterally into the neural lobe. The results call into question previous reports on the presence of AVP on receptors in the pars intermedia cells, since incubation with anti-AVP resulted in similar staining in the pars intermedia of the Wistar and homozygous Brattleboro rat, a mutant strain deficient in AVP. The same intermediate lobe cells are stained after incubation of serial sections with anti-AVP and anti-α-melanocyte-stimulating hormone (α-MSH). This staining of anti-AVP could be removed by solid phase absorption to α-MSH and is thus most probably due to cross reaction with α-MSH. SOM fibres appear to be present in the peripheral parts of the proximal neurohypophysial stalk and mainly lateral in its more distal parts. In the neural lobe they rapidly decrease in number, although some fibres continue into the distal part of the neural lobe, running bilaterally and situated adjacent to the pars intermedia. The SOM staining within magnocellular elements, which has been reported in the literature, can most probably be explained by cross reaction of anti-SOM with neurophysins. LHRH fibres are very scarce in the neurohypophysial stalk and absent in the neural lobe.Vir: Cell and tissue research. - ISSN 0302-766X (Vol. 202, no. 2, 1979, str. 189-201)Vrsta gradiva - članek, sestavni del ; neleposlovje za odrasleLeto - 1979Jezik - angleškiCOBISS.SI-ID - 157157123
Avtor
Leeuwen, W. van |
Raay, C. de |
Fisser, B.
Teme
hormones |
neurohypophysis |
rats |
hormoni |
nevrohipofiza |
podgane
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Leeuwen, W. van | ![]() |
Raay, C. de | ![]() |
Fisser, B. | ![]() |
Vir: Osebne bibliografije
in: SICRIS
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