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  • Chromosome aberrations study of pupils in high radon level elementary school
    Bilban, Marjan ; Vaupotič, Janja
    The ICRP Publication 65 recommends 200-600 Bq m(-3) as the indoor radon actionlevel for the general public. In Slovenia, a value of 400 Bq m(-3) has been proposed but not yet approved. In a ... nation-wide radon project financed by the Health Inspectorate of Slovenia, it was discovered that the elementary school named "S3" belongs to a group of schools with elevated winter indoor radon concentrations up to 7,000 Bq m(-3). Opening windows and doors during classes substantially decreased radon concentrations, but very seldom below 1,000 Bq m(-3). Yearly effective doses for pupils, estimated according to ICRP 65, ranged from 7 to 11 mSv. Because the pupils have been subjected to the elevated radon concentrations, special preventive health checks have been performed. The examination protocol included mutagenetic tests, one for structural chromosomal aberrations and the other a micronucleus test. Altogether 85 pupils (37 girls and 48 boys) from the first four grades between the ages of 9 and 12 y were examined. An increase in cytogenetic damage was found for these pupils, compared to the control group, composed of pupils of the same age from another area with indoor radon concentrations in their school of below 400 Bq m(-3). The incidence of structural chromosomal aberrations reached 2.0% (0.5-4) and micronucleus test was 6.52 per 500 cells with a maximum of 15 in some cases. In the control group structural chromosomal aberrations varied from 0.5 to 2.5%, while the maximum incidence of micronucleus was 9 micronucleus per 500 CB cells. Theresults obtained are preliminary and suggest a need to expand the study. A long-term radon survey, at least over a year, of the homes and wider residential environment of the pupils would be necessary to assess the correlation between radon exposure and both structural chromosomal aberrations and micronucleus findings.
    Vir: Health physics. - ISSN 0017-9078 (Vol. 80, 2001, str. 157-163)
    Vrsta gradiva - članek, sestavni del
    Leto - 2001
    Jezik - angleški
    COBISS.SI-ID - 15879719

vir: Health physics. - ISSN 0017-9078 (Vol. 80, 2001, str. 157-163)
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