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  • The role of radioactive iodine in the treatment of Hürthle cell carcinoma of the thyroid
    Bešić, Nikola ...
    It is generally believed that Hurthle cell thyroid carcinoma (HCTC) does not accumulate radioactive iodine (RAI). The aim of our retrospective study was tofind out if, after thyroid surgery and RAI ... ablation of the thyroid remnant, the metastatic or recurrent HCTC accumulates RAI. We reviewed the charts of 48patients with histopathologically verified HCTC, who were treated at the Institute of Oncology in Ljubljana, Slovenia, from 1972 to 2000. In 16 patients (11 women, five menč 47-77 years old), who had distant metastases at presentation (eight patients) or recurrence (eight patients), whole-body RAI scanning was performed after the withdrawal of thyroid hormone replacement. Whenever RAI uptake was confirmed, the therapy with 5.6 GBq of RAI was performed. In 11 of 16 patients, the uptake (range 0.1-12%) of RAI was confirmed. Altogether, 46 therapeutic applications of RAI were given. We conclude that whole-body scanning with RAI should be performed in HCTC. RAI may be effective in the treatment of HCTC.
    Vir: Thyroid. - ISSN 1050-7256 (Letn. 13, št. 6, 2003, str. 577-584)
    Vrsta gradiva - članek, sestavni del
    Leto - 2003
    Jezik - angleški
    COBISS.SI-ID - 16843737

vir: Thyroid. - ISSN 1050-7256 (Letn. 13, št. 6, 2003, str. 577-584)
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