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  • Low serum pancreatitis-associated protein does not exclude complications in mild acute pancreatitis
    Polanec, Janja ...
    Normal serum PAP levels on admission to the hospital in patients with acute pancreatitis has been proposed to help select tha patients who are not going to develop complications. The aims of this ... study were,first, to assess the specifity of serum pancreatitis-associated protein (PAP) serology test and second, to evaluate the usefulness of the test for predicting complications in acute pancreatitis on admission to the hospital. The sensitivity of the PAP ELISA in patien[t]s with acute pancreatitis on admission to the hospital was 70% and the serum PAP levels significantly higher than in healthy controls (p<0.0001). However, the serum PAP levels in patients with acute pancreatitis were not significantly different from values in patients with various abdominal diseases (p<0.58). Serum PAP levels gave good correlation toAPACHE II (p=0.02) and CRP (p=0.01). Two patients with local complications (necrotizing pancreatitis, pancreatic fluid collection) has elevated serum PAP levels on admission to the hospital (>100 ng/ml). The diagnostic specifity of PAP ELISA is low. Patients, who develop local complications in acute pancreatitis can not be excluded by normal serum PAP levels on admission to the hospital.
    Vir: Pathology oncology research. - ISSN 1219-4956 (Vol. 3, no. 1, 1997, str. 30-33)
    Vrsta gradiva - članek, sestavni del ; neleposlovje za odrasle
    Leto - 1997
    Jezik - angleški
    COBISS.SI-ID - 168561