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  • Transplantacija jeter kot način zdravljenja malignih jetrnih tumorjev
    Stanisavljević, Dragoje ; Mekizar, Jernej
    The most common liver cancers are hepatocellular carcinoma, cholangiocellular carcinoma and metastatic cancer. Despite recent advances with techniques of insitu tumor ablation, surgical therapy ... remains at present the mainstay in thetreatment of hepatic malignancies. After an initial endeavor to establish liver transplantation as a treatment option, especially for unresectable livertumors, only a few indications, for example early hepatocellular carcinoma in cirrhosis, are currently agreed upon. Other indications, such as peripheral cholangiocarcinoma and hepatocellular carcinoma in non-cirrhotics, have largely been abandoned or are still under debate. Selection of patients suffering from hepatocellular carcinoma in cirrhosis for liver transplantationis still based on tumor size and node number, because the current state of diagnostic imaging fails to reliably predict the most important prognostic parameter: vascular infiltration. Surgical resection including repeated hepatectomy indicates better survival in patients with liver metastases. Only in some patients with irresectable neuroendocrine hepatic metastases, liver transplantation may provide not only longterm palliation but even cure. Regarding the shortage of donor organs, liver grafting for neuroendocrine metastases should be considered solely in patientswithout evidence of extrahepatic tumor manifestation and in whom all other treatment methods are no longer effective.
    Vir: Gastroenterolog : revija Slovenskega združenja za gastroenterologijo in hepatologijo = journal of Slovenian Association for Gastroenterology and Hepatology. - ISSN 1408-2756 (Letn. 7, št. 3, 2003, str. 55-63)
    Vrsta gradiva - članek, sestavni del
    Leto - 2003
    Jezik - slovenski
    COBISS.SI-ID - 17140697

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