Akademska digitalna zbirka SLovenije - logo
VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • Kratek pregled tumorskih cepiv in naše izkušnje = A brief overview of the current status of tumor vaccines and our experience in this line of work
    Novaković, Srdjan
    Tumor vaccines represent a category of biological (immune) therapies through which we try to trigger an effective systemic immune response against tumor antigens and thus against all cancer cells. ... Accordingly, the effect of tumor vaccines depends upon: presence/absence of recognizable tumor antigens, presence of co-stimulatory molecules, which cooperate in the activation of effector cells, presenting of antigens and co-stimulatory molecules to the effector cells, development of specific immunity, and development of mechanisms by which tumor cells escape immune surveillance. With regard to thebasic principles of vaccine development and their expected activity, tumor vaccines can be divided into two subclasses: first-generation vaccines whichare based on the principles of classical immunology - i. e. classical rumor vaccines, and second-generation vaccines which are based on the principles of molecular immunology genetically modified and recombinant tumor vaccines. This article gives a short review of the major concepts for the development of tumor vaccines, as well as of ongoing research at the Instituteof Oncology.
    Vir: Medicinski razgledi. Supplement. - ISSN 0353-3484 (Letn. 43, suppl. 5, 2004, str. 63-68)
    Vrsta gradiva - prispevek na konferenci
    Leto - 2004
    Jezik - angleški
    COBISS.SI-ID - 18595289

vir: Medicinski razgledi. Supplement. - ISSN 0353-3484 (Letn. 43, suppl. 5, 2004, str. 63-68)
loading ...
loading ...
loading ...