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  • Microbiological Quality Assurance of Purified Water by Ozonization of Storage and Distribution System
    Florjanič, Maja ; Kristl, Julijana
    Purified water storage and distribution systems at ambient temperature are highly susceptible to microbial contamination and formation of biofilm. The impact of two disinfection regimens with ozone ... as a function of time, the heterotrophic plate counts (HPC), and the concentration of total organic compounds (TOC) in purified water were investigated over a period of 4 years. We have established that concentrations of ozone of 70 20 ppb in the production regimen and 250 50 ppb in the disinfection regimen are sufficientto maintain a low bioburden and low TOC in a recirculating distribution system. The purified water that entered into the distribution system has low HPC (0.01 CFUžmL), indicating a reduction by ozone in the storage tank by up to approximately 120-fold. Over 4 years, 94-98% of the microbial counts were in the category 0-5 CFUžmL, and none in category 50 CFUžmL. In spite of increased TOC in the inlet water, up to 40 ppb, the microbial counts in purified water in the distribution loop were unaffected. The study emphasizes that the critical points regarding microbial contamination of the purified water system are user point valves and the tubesused for transferring water to equipment. The specified ozone level prevents microbial growth and formation of biofilm in the distribution system that might otherwise endanger the water quality by sporadic release of microbes.
    Vir: Drug development and industrial pharmacy. - ISSN 0363-9045 (Vol. 32, no. 10, 2006, str. 1113-1121)
    Vrsta gradiva - članek, sestavni del
    Leto - 2006
    Jezik - angleški
    COBISS.SI-ID - 1999985

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