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  • Spremljanje občutljivosti invazivnih izolatov bakterije Streptococcus pneumoniae za antibiotike v Sloveniji = The antimicrobial susceptibility in invasive isolates of bacteria Streptococcus pneumoniae in Slovenia
    Paragi, Metka, 1962- ...
    Streptococcus pneumoniae is among the most significant causes of bacterial invasive diseases in humans. During the observed period (from 2002 to 2005), the incidence of pneumococcal infections in ... Slovenia increased, especially among adult patients. The resistance figures were twice as high in children asin adult patients. A significant rise in antibiotic resistance has been observed since 2002, especially in the year 2004. In 2005, a decrease in resistance to penicillin, trimethoprim/sulfamethoxazole, tetracycline and erythromycin was observed. Isolates showing resistance to penicillin among adult patients belonged to serotypes 14, 9V, 19F and 19A, while 6B was more frequent in children. We identified the molecular basis of macrolide resistance. The prevalent mechanism resulted from the presence of the erm(B) (59%) gene, followed by the mef (33%) gene. A correlation was found between the erm(B) gene and serotype 6B, and between the mef gene and serotype 14.
    Vrsta gradiva - prispevek na konferenci
    Leto - 2006
    Jezik - slovenski
    COBISS.SI-ID - 21288409