Akademska digitalna zbirka SLovenije - logo
VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • Quality control assessment for the serological diagnosis of tick borne encephalitis virus infections
    Niedrig, Matthias ...
    Background: The diagnosis of tick borne encephalitis (TBE) is mainly based on the demonstration of specific antibodies in serum when neurological disease ismanifested. Improving diagnostics is the ... most important step in detecting and dealing with these pathogens. Quality control measures are essential for TBE diagnosis. Objective: To assess an external quality assurance (EQA) program for the serologic diagnosis of TBE infections. Study design: A panel of 12 serum samples was sent out to be tested for the presence of TBE virus-specific IgM and IgG. This panel contained seven TBE-positive samples for IgM and/or IgG; three negative samples; two samples positive either for West Nile virus (WNV) or Dengue virus (DENV). Results: Fourty-two laboratoriesfrom 25 European and 2 non-European countries participated in thisEQA. The correct answer by each laboratory for all samples ranked between 58 and 96% and sera with IgM antibody positive for TBE were correctly recognized by 46-88% of the laboratories. Sera with IgG antibody positive for TBE were correctly recognized by 83-95% of the laboratories. False TBE-positive results were obtained with DENV, WNV or negative sera only for IgG-based assays. Conclusion: Correct results for at least 90% of the samples were obtained by 33 of 40 participating laboratories for IgM and for 16 of 42 laboratories for IgG.
    Vir: Journal of clinical virology. - ISSN 1386-6532 (Letn. 38, št. 3, 2007, str. 260-264)
    Vrsta gradiva - članek, sestavni del
    Leto - 2007
    Jezik - angleški
    COBISS.SI-ID - 22636505

vir: Journal of clinical virology. - ISSN 1386-6532 (Letn. 38, št. 3, 2007, str. 260-264)
loading ...
loading ...
loading ...

Vnos na polico