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  • The thymus is a source of B-cell-survival factors-APRIL and BAFF-in myasthenia gravis
    Thanggarajh, Mathula ...
    The accumulation of B cells in the thymus is a common feature of myasthenia gravis (MG). To understand whether factors enhancing B-cell survival are increased in MG, we studied the expression of ... APRIL, BAFF and three of their receptors in the thymus. In hyperplastic thymi, macrophages expressed APRIL and BAFF, and germinal-center B cells, BAFF-R. CD138-positive plasma cells were abundant in MG thymi. By contrast, BCMA-positive plasma cells were scarce. The expression of APRIL and BAFF in MG thymi may reflect the establishment of an environment favorable to B-cell survival.
    Vir: Journal of neuroimmunology. - ISSN 0165-5728 (Letn. 178, št. 1/2, 2006, str. 161-166)
    Vrsta gradiva - članek, sestavni del
    Leto - 2006
    Jezik - angleški
    COBISS.SI-ID - 24548825
    DOI

vir: Journal of neuroimmunology. - ISSN 0165-5728 (Letn. 178, št. 1/2, 2006, str. 161-166)
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