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  • Ventricular repolarization dynamicity and arrhythmic disturbances after beating-heart and arrested-heart revascularization
    Kališnik, Jurij-Matija ...
    Background: Arrhythmias attributable to altered autonomic modulation of the heart, with elevated sympathetic and depressed vagal modulation, occur to a similar extent after surgery performed on ... beating or arrested hearts. Coronaryartery bypass grafting (CABG) with cardiopulmonary bypass has been associated with more frequent occurrence of arrhythmic events than surgery performed without CABG, even with comparable levels of postoperative cardiac autonomic (dis) regulation after arrested- and beating-heart revascularization. We explored the effects of arrested- and beating-heart revascularization procedures on the dynamics of ventricular repolarization andon increased postoperative arrhythmic events.Methods: Study participants included 57 CABG patients; 28 underwent on-pump and 29 underwent off-pump procedures. The 2 groups were comparable regarding clinical and postoperative characteristics. With high-quality 15-minute digital electrocardiograms, we assessed ventricular repolarization dynamics using RR and QT intervals and analyzed QT variability (QTV) and QT-RR interdependence. RR and QT intervals were determined from stationary 5-minute segments. QT-interval variability wasdetermined by a T-wave template-matching algorithm. We used linear regression to compute the slope/correlation of the QT/RR interval. The Fisher exact test, nonpaired t-test, and ANOVA were applied to test the results; P <.05 was considered significant.Results: Postoperative arrhythmic events were significantly more frequent in both groups. One week postoperatively these events were significantly more frequent in the on-pump group. In both groups, the RR interval was shorter after CABG (P <.001). The QT variability index increased from -1.2 +/- 0.6 to -0.8 +/- 0.4 after off-pump CABG and from -1.3 +/- 0.5 to -0.5 +/- 0.6 on day 4 after surgery (P <.05), further deterioratingto -0.2 +/- 0.6 one week after CABG in the on-pump group only (P <.05). (Abstract trunc
    Vir: The heart surgery forum. - ISSN 1098-3511 (Letn. 11, št. 4, 2008, str. E194-E201)
    Vrsta gradiva - članek, sestavni del
    Leto - 2008
    Jezik - angleški
    COBISS.SI-ID - 24802521
    DOI

vir: The heart surgery forum. - ISSN 1098-3511 (Letn. 11, št. 4, 2008, str. E194-E201)
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