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  • Thymidine kinases in archaea
    Clausen, Anders Renegaard ...
    Twenty-six fully sequenced archaeal genomes were searched for genes coding forputative deoxyribonucleoside kinases (dNKs). We identified only 5 human-like thymidine kinase 1 genes (TK1s) and none for ... non-TK1 kinases. Four TK1s were identified in the Euryarchaea and one was found in the Crenarchaea, while none was found in Nanoarchaeum. The identified TK1s have high identity to Gram-positive bacteria TK1s. The TK1s from archaea, Gram-positive bacteria and eukaryotes share the same common ancestor, while the TK1s from Gram-negative bacteria belong to a less-related subgroup. It seems that a functional deoxyribonucleoside salvage pathway is not crucial for the archaealcell.
    Vir: Nucleosides, nucleotides & nucleic acids. - ISSN 1525-7770 (Letn. 25, št. 9-11, 2006, str. 1159-1163)
    Vrsta gradiva - članek, sestavni del
    Leto - 2006
    Jezik - angleški
    COBISS.SI-ID - 25359321
    DOI

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