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  • Syringotropic hypersensitivity reaction associated with infliximab and leflunomide combination therapy in a child with psoriatic arthritis
    Vesel, Tina, 1974- ...
    A 17-year-old boy with refractory psoriatic arthritis and alpha-1 antitrypsin deficiency who developed a syringotropic hypersensitivity reaction after 9 months of therapy with infliximab and ... leflunomide is described. Clinically, our patient showed a vasculitic-like skin rash involving both palms and soles, and histopathological examination revealed a syringotropic lymphocytic infiltrate directed toward the intra-epidermal portion of the eccrine ducts. These features have not been previously associated with infliximab or leflunomide therapy and represent a unique cutaneous hypersensitivity reactionthat does not fit any known description of an immune-mediated hypersensitivity reaction. Vesel T, Luzar B, Calonje E, Avcin T. Syringotropichypersensitivity reaction associated with infliximab and leflunomide combination therapy in a child with psoriatic arthritis.
    Vir: Journal of cutaneous pathology. - ISSN 0303-6987 (Letn. 36, 2009, str. 991-994)
    Vrsta gradiva - članek, sestavni del
    Leto - 2009
    Jezik - angleški
    COBISS.SI-ID - 25781977
    DOI