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  • European registry of babies born to mothers with antiphospholipid syndrome : a result update
    Boffa, Marie-Claire ...
    The registry is a prospective, European, multicentric, longitudinal study, which follows a cohort of children born to mothers with antiphospholipid syndrome (APS). It was started in 2003. In this ... report, we update the results obtained from the study of 110 mothers and 112 children (two twin births). Eighty per cent of the mothers (n = 86) had primary APS. Purely obstetrical, thrombotic and mixed (obstetrical and thrombotic) APS represent 65.5 %, 21.8 %and 12.7 % of the whole cohort respectively. Isolated antiphospholipid antibodies and isolated anticardiolipin antibodies positivity were present in 50 of 109 (46%) and in 34 of 109 (31%) of the pregnant women, respectively. Inthe babies, in spite of a high rate of prematurity (14.3%) with four (3.6%) of the premature babies born before 33 weeks of gestation and an increased number of newborns small for gestational age (17%), the large majority of the neonates were healthy. Thirty-one infants are now older than 24 months. Among them, three displayed behavioural abnormalities before 3 years of age. After completing data, there will be the possibility to evaluate the newborn status in relation to the mothersć diseases, treatments and antibodies and to follow the neuropsychological development and immunological evolution of the babies during the next 5 years.
    Vir: Lupus. - ISSN 0961-2033 (Letn. 18, št. 10, 2009, str. 900-904)
    Vrsta gradiva - članek, sestavni del
    Leto - 2009
    Jezik - angleški
    COBISS.SI-ID - 25794009
    DOI

vir: Lupus. - ISSN 0961-2033 (Letn. 18, št. 10, 2009, str. 900-904)
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