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  • Gut health promoting activity of new putative probiotic/ protective Lactobacillus spp. strains : a functional study in the small intestinal cell model
    Nissen, Lorenzo ...
    In interaction studies with the host intestine, the use of the appropriate gutfunctional cell model is essential. Therefore, we examined the protective properties of selected lactobacilli in a newly ... established intestinal cell model. Bacteria were cocultured with the pig small intestinal epithelial cells(PSlc1) and pig blood monocytes (PoM2) in a fnctional intestinal cell model. Intercellular intestinal integrity was measured by transepithelial electric resistance (TER), before and after coculture with selected bacterial strains. All selected bacterial strains showed important gut health promoting activity by: enhancing the intestinal integrity and incresing matablic activity of intestinal cells. Stimulation of immune response was strain specific. Th best stimulats were unidentified lactobacillus strains obtained from fermented food in Africa (PCK87 and 66), followed by Lactobacillus plantarum (PCS26). Their activity was significantly higher (p<0.05) than that of the commercial Lactobacillus casei Shirota strain.
    Vir: International journal of food microbiology. - ISSN 0168-1605 (Letn. 135, št. 3, 2009, str. 288-294)
    Vrsta gradiva - članek, sestavni del
    Leto - 2009
    Jezik - angleški
    COBISS.SI-ID - 2839340

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