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  • Clinical use of cellular test in personalized allergy management
    Korošec, Peter, 1970-
    Through development of flow cytometry, discovery of activation markers such as CD63 and markers identifying basophil granulocytes in the last decade the basophil activation test (BAT) has become a ... multifaceted and accessible tool for the allergist. In patients with insect venom, food and drug allergy BAT can be part of the diagnostic evaluation in addition to history, skin testing and specific IgE deter - mination. The basophil sensitivity can be used to monitor patients on allergen immunotherapy, anti-IgE treatment or in the natural resolution of allergy. A very important recent data demonstrated that the BAT can be used to estimate the severity and threshold of allergic reactions to peanut and insect venom and that can be efficiently upgraded with the use of recombinant allergens. The nature of BAT, as a highly quantitative ex vivo challenge test, makes them as the most important cellular test in personalized allergy management.
    Vir: Personalised medicine in respiratory and immunologic diseases : book of abstracts (Str. 90-93)
    Vrsta gradiva - prispevek na konferenci
    Leto - 2016
    Jezik - angleški
    COBISS.SI-ID - 288727040

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    http://www.klinika-golnik.si/uploads/si/strokovna-javnost/strokovne-publikacije/6-slovenian-pneumology-congress-book-of-abstracts-194.pdf

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