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  • Primerjava patogenosti zelo virulentnega in blagega virusa gumborske bolezni pri SPF piščancih = Pathogenicity of highly virulent isolate of infectious bursal disease virus (IBDV) in comparison with vaccinal strain of IBDV in specific pathogen free chickens
    Zorman-Rojs, Olga ; Černe, Manica
    Specific - pathogen free chickens inoculated with the field strain of IBDV andwith the so called mild - vaccinal strain of IBDV were examined in order tocharacterise the pathogenicity of the field ... isolate of IBDV. Field isolate of IBDV induced severe clinical disease in two days, the course of disease wasshor with high morbidity and mortality. Besides very characteristic macroscopic lesions on bursaes, muscles, provetriculus and kidneys the study revealed distinct differences between both viruses also in microscopic changeson bursa and in non bursal haemopoetic organs. highly virulent field isolte induced very intensive lesions of a long durationin bursa which were seen in focal limphoid necroses, haemorrhages of the field isolate was also its abbility to induce severe thymic lesions accompanied with inflammatory reactions in the lung, spleen, ileocaecal tonsil and bone marrow, which was not the case when mild strain of IBDV was used as challenge virus. There were no difference in specific humoral response to IBDV between both tested viruses.
    Vrsta gradiva - članek, sestavni del
    Leto - 1997
    Jezik - slovenski, angleški
    COBISS.SI-ID - 294778