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  • Use of sealed grafts In The Heartmate II Left Ventricular Assist Device Inflow and outflow conduits
    Gregorič, Igor ...
    Gelatin impregnated non-porous sealed grafts were introduced in the inflow and outflow conduits for use with the HeartMate II (HMII) to eliminate pre-clotting procedures and to reduce operative ... bleeding.We compared results of 67 patients who received first time LVADs with sealed inflow and outflow grafts (S-graft group) to a preceding 65 patients who received an LVAD with non-sealed grafts (NS-graft group).Overall, the amount of blood product transfusions was less in the S-graft group than in the NS-graft group (red blood cells, 4.9 % 4.5 vs. 8.0 % 9.4 units, P=0.022; fresh frozen plasma, 5.0 % 3.0 vs. 8.7 % 9.3 units, P=0.004; platelets, 2.9 % 1.1 vs. 4.5 % 3.5 units, P=0.001; and cryoprecipitate, 1.2 % 0.9 vs. 2.01 % 1.9 units, P=0.002). Within a follow-up period of 6 months, no device-related infections or strokes occurred in the S-group, but the NS-group had 1 (1.5%) driveline infections and 4 (6%) strokes. The 30-day survival rate was not significantly different between groups (P=0.053), but favored the S-group (97%) over the NS-group (88%). Use of a HMII with a sealed graft on the inflow and outflow conduits is associated with less postoperative bleeding, and may have helped to decrease the frequency of postoperative adverse events.
    Vir: ASAIO journal. - ISSN 1058-2916 (Vol. 60, iss. 3, May/Jun. 2014, str. 300-303)
    Vrsta gradiva - članek, sestavni del
    Leto - 2014
    Jezik - angleški
    COBISS.SI-ID - 31264473
    DOI

vir: ASAIO journal. - ISSN 1058-2916 (Vol. 60, iss. 3, May/Jun. 2014, str. 300-303)
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