Akademska digitalna zbirka SLovenije - logo
VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
PDF
  • Targeting the latent reservoir to achieve functional HIV cure [Elektronski vir] : [version 1; referees: 3 approved]
    Cary, Daniele C. ; Peterlin, Matija Boris
    While highly active anti-retroviral therapy has greatly improved the lives of HIV-infected individuals, current treatments are unable to completely eradicate the virus. This is due to the presence of ... HIV latently infected cells which harbor transcriptionally silent HIV. Latent HIV does not replicate or produce viral proteins, thereby preventing efficient targeting by anti-retroviral drugs. Strategies to target the HIV latent reservoir include viral reactivation, enhancing host defense mechanisms, keeping latent HIV silent, and using gene therapy techniques to knock out or reactivate latent HIV. While research into each of these areas has yielded promising results, currently no one mechanism eradicates latent HIV. Instead, combinations of these approaches should be considered for a potential HIV functional cure.
    Vir: F1000Research. - ISSN 2046-1402 (Vol. 5, 2016, str. 1-8)
    Vrsta gradiva - e-članek
    Leto - 2016
    Jezik - angleški
    COBISS.SI-ID - 33121241

    Povezava(-e):

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882755/pdf/f1000research-5-8724.pdf
    DOI

Vnos na polico