VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
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Substantial underdiagnosis of lymphogranuloma venereum in men who have sex with men in Europe : preliminary findings from a multicentre surveillance pilotCole, Michelle Jayne ...ObjectivesUnderstanding the public health impact of lymphogranuloma venereum (lgV) in europe is hampered by inadequate diagnostics and surveillance systems in many european countries. We developed ... and piloted lgV surveillance in three european countries without existing systems and performed a preliminary investigation of lgV epidemiology, where little evidence currently exists.MethodsWe recruited Sti or dermatovenereology clinics and associated laboratories serving men who have sex with men (MSM) in austria, croatia and Slovenia, using the UK for comparison. We undertook centralised lgV testing of Chlamydia trachomatis (ct)-positive rectal swabs collected between October 2016 and May 2017 from MSM attending these clinics. Stored specimens from austria (2015%2016) and croatia (2014) were also tested. clinical and sociodemographic data were collected using a standardised proforma. the ompA gene of lgV-positive specimens was sequenced.resultsin total, 500 specimens from ct-positive MSM were tested, and lgV positivity was 25.6% (128/500; 95% ci 22.0% to 29.6%) overall, and 47.6% (79/166; 40.1% to 55.2%) in austria, 20.0% (3/15; 7.1% to 45.2%) in croatia, 16.7% (1/6; 3.0% to 56.4%) in Slovenia and 14.4% (45/313; 10.9% to 18.7 %) in the UK. Proformas were completed for cases in croatia, Slovenia and in the UK; proformas could not be completed for austrian cases, but limited data were available from line listings. Where recorded, 83.9% (78/93) of lgV-ct cases were HiV-positive compared with 65.4% (149/228) of non-lgV-ct cases; MSM with lgV-ct were more likely to have proctitis (austria, 91.8% vs 40.5%, p<0.001; croatia, 100% vs 25%, p=0.04; UK, 52.4% vs 11.7%, p<0.001) than those with non-lgV-ct. Six different ompA sequences were identified, including three new variants; the l2 ompAsequence predominated (58.6%, 51/87).ConclusionslgV is substantially underdiagnosed in MSM across europe. Unified efforts are needed to overcome barriers to testing, establish effective surveillance, and optimise diagnosis, treatment and prevention.Vir: Sexually transmitted infections. - ISSN 1368-4973 (Vol. 96, no. 2, Mar. 2020, str. 137-142)Vrsta gradiva - članek, sestavni del ; neleposlovje za odrasleLeto - 2020Jezik - angleškiCOBISS.SI-ID - 34389721
Avtor
Cole, Michelle Jayne |
Field, Nigel |
Pitt, Rachel |
Amato-Gauci, Andrew |
Begovac, Josip |
French, Patrick D |
Keše, Darja, 1959- |
Klavs, Irena |
Židovec-Lepej, Snježana |
Pöcher, Katharina
Teme
lymphogranuloma venereum |
sex with men |
men |
lymphogranuloma venereum |
spolni odnosi z moškimi |
moški
Vnos na polico
Trajna povezava
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Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Cole, Michelle Jayne | |
Field, Nigel | |
Pitt, Rachel | |
Amato-Gauci, Andrew | |
Begovac, Josip | |
French, Patrick D | |
Keše, Darja, 1959- | 05381 |
Klavs, Irena | 07782 |
Židovec-Lepej, Snježana | |
Pöcher, Katharina |
Vir: Osebne bibliografije
in: SICRIS
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