Akademska digitalna zbirka SLovenije - logo
VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • Transcatheter replacement of transcatheter versus surgically implanted aortic valve bioprostheses
    Landes, Uri ...
    Surgical aortic valve replacement and transcatheter aortic valve replacement (TAVR) are now bothused to treat aortic stenosis in patients in whom life expectancy may exceed valve durability. The ... choice of initial bio-prosthesis should therefore consider the relative safety and efficacy of potential subsequent interventions.Objectives The aim of this study was to compare TAVR in failed transcatheter aortic valves (TAVs) versus surgical aortic valves (SAVs). Methods Data were collected on 434 TAV-in-TAV and 624 TAV-in-SAV consecutive procedures performed at centersparticipating in the Redo-TAVR international registry. Propensity score matching was applied, and 330 matched (165:165)patients were analyzed. Principal endpoints were procedural success, procedural safety, and mortality at 30 days and 1 year.Results For TAV-in-TAV versus TAV-in-SAV, procedural success was observed in 120 (72.7%) versus 103 (62.4%)patients (p-0.045), driven by a numerically lower frequency of residual high valve gradient (p-0.095), ectopic valvedeployment (p-0.081), coronary obstruction (p-0.091), and conversion to open heart surgery (p-0.082). Proce-dural safety was achieved in 116 (70.3%) versus 119 (72.1%) patients (p-0.715). Mortality at 30 days was 5 (3%) afterTAV-in-TAV and 7 (4.4%) after TAV-in-SAV (p-0.570). At 1 year, mortality was 12 (11.9%) and 10 (10.2%), respectively(p-0.633). Aortic valve area was larger (1.55+-0.5 cm2vs. 1.37+-0.5 cm2;p-0.040), and the mean residual gradientwas lower (12.6+-5.2 mm Hg vs. 14.9+-5.2 mm Hg; p-0.011) after TAV-in-TAV. The rate of moderate or greaterresidual aortic regurgitation was similar, but mild aortic regurgitation was more frequent after TAV-in-TAV (p-0.003).ConclusionsIn propensity score-matched cohorts of TAV-in-TAV versus TAV-in-SAV patients, TAV-in-TAV wasassociated with higher procedural success and similar procedural safety or mortality.
    Vir: Journal of the American College of Cardiology. - ISSN 0735-1097 (Vol. 77, is. 1, Jan. 2021, str. 1-14)
    Vrsta gradiva - članek, sestavni del ; neleposlovje za odrasle
    Leto - 2021
    Jezik - angleški
    COBISS.SI-ID - 43775747
    DOI

Vnos na polico