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  • Confirming the concept for prediction and control of unimolecular G-quadruplex formation
    Trajkovski, Marko, 1984- ...
    Guanine rich DNA sequences can form G-quadruplexes - four stranded structures consisting of stacks of basic structural elements called G-quarters in which four guanines are H-bonded. The concept of ... predicting and controlling G-quadruplex formation was tested on obligonucleotide sequence d[G3TG3T4G3T3G3], which was predicted to fold into a single topology. The self-assembly of the oligonucleotide is controlled through disposition of guanine conformations in G-quadruplex stem, which is directed by optimally choosing the loop lengths.
    Vrsta gradiva - prispevek na konferenci
    Leto - 2010
    Jezik - angleški
    COBISS.SI-ID - 4437530