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  • Application of ▫$^10B$▫ entrapped PEG-liposome to boron nautron-capture therapy for pancreatic cancer model in vivo
    Yanagie, H. ...
    The cytotoxic effects for tumor were evaluated with intraveneous injection ▫$^10B$▫ PEG-liposome (Sealth liposome)on human pancreatic carcinoma xenografts in nude mice with thermal neutron ... irradiation. After thermal neutron irridation of mice injected with ▫$^10B$▫ bare liposome or ▫$^10B$▫ PEG-liposome, AsPC-1 tumor growth was suppressed relative to controls. Injection of ▫$^10B$▫ PEG-liposome caused the greatest tumor suppression with thermal neutron irradiation in vivo. These results suggest that intravenous injection of ▫$^10B$▫ PEG-liposome can increase the retention of ▫$^10B$▫ atoms by tumor cells, causing tumor growth suppression in vivo upon thermal neutron irradiation.
    Vir: Proceedings (Str. 709-715)
    Vrsta gradiva - prispevek na konferenci
    Leto - 1999
    Jezik - angleški
    COBISS.SI-ID - 5045782

vir: Proceedings (Str. 709-715)
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